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Methyl (methylthio)acetate CAS: 16630-66-3

Methyl (methylthio)acetate CAS: 16630-66-3

Methyl (methylthio)acetate, with CAS number 16630-66-3, is a high-purity organic sulfur compound. It serves as a versatile building block in pharmaceutical synthesis (for heterocyclic compounds) and is also utilized as a raw material in the flavor and fragrance industry. As a professional supplier, we provide consistent quality with strictly controlled acid value and moisture content to support diverse industrial applications.

  • Product Name :

    Methyl (methylthio)acetate
  • CAS No. :

    16630-66-3
  • Application :

    Thifensulfuron intermediates
  • Description
Methyl (methylthio)acetate is colorless liquid, a high-purity ester-type organosulfur compound. As a multifunctional synthetic building block, it exhibits unique chemical activity in constructing sulfur-containing heterocyclic compounds. Simultaneously, due to its distinctive olfactory characteristics, it is also used in the formulation of daily chemical and food flavorings. We employ an advanced continuous esterification process to ensure the product has a low acid value, pure aroma (no burnt smell), and strictly control moisture content, meeting the dual standards of the fine chemical and fragrance industries.
 

Properties

Product: Methyl (methylthio)acetate

CAS:  16630-66-3

Molecular Formula:C4H8O2S

Molecular Weight:120.17 g/mol

Appearance:colorless liquid

Boiling Point:144-145 °C (lit.)

Refractive index:n20/D 1.463 (lit.)

Density:1.12 g/mL at 25 °C (lit.)

Solubility:Soluble in ethanol, ether, and ethyl acetate; insoluble in water.

 

 

Specification

Items Specifications
Appearance colorless liquid
Purity 99.9563%min

 

Applications

 

DUDLEY’s Methyl thioacetate (CAS: 16630-66-3) is used in both the fine chemical and fragrance industries.

 

1. Pharmaceutical and Pesticide Intermediates:

Heterocyclic Synthesis: Utilizing the active methylene and ester groups in their molecules, Claisen condensation or cyclization reactions can be performed to synthesize sulfur-containing heterocyclic derivatives such as thiophenes and thiazoles. These structures are widely found in antibacterial and anti-inflammatory drugs.

 

Functional Group Conversion: They can serve as donors for methyl thio (-SMe) groups or be used to prepare corresponding sulfoxide/sulfone intermediates through oxidation.

2. Flavors & Fragrances:

Edible Flavors: Used at very low concentrations to formulate edible flavors with tropical fruit (such as pineapple, durian) or specific vegetable (such as potato, onion) flavors.

 

Chemical Flavors: Used to formulate certain chemical fragrance bases with special styles.

      

Package

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