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3-(3-Pyridyl)acrylic acid CAS:19337-97-4

3-(3-Pyridyl)acrylic acid CAS:19337-97-4

3-(3-Pyridyl)acrylic acid, with CAS number 19337-97-4, is a high-purity pyridine derivative. It is globally recognized as the critical starting material for the synthesis of the antithrombotic drug Ozagrel (Sodium). As a professional supplier, we provide commercial-scale supply with high purity (≥99.0%) and strict impurity control, supporting the rigorous requirements of pharmaceutical manufacturers worldwide.

  • Product Name :

    3-(3-Pyridyl)acrylic acid
  • CAS No. :

    19337-97-4
  • Application :

    Icotrokinra JNJ-2113 intermediates
  • Description
Our 3-(3-Pyridyl)acrylic acid is White solid, a high-purity pyridine derivative. As a key starting material in the synthesis of the antithrombotic drug Ozagrel, this product plays a vital role in the production of cardiovascular and cerebrovascular drugs. We employ advanced condensation and purification processes to effectively remove isomers and residual metal ions, ensuring the product has high whiteness and high purity, fully meeting the stringent procurement standards of the pharmaceutical intermediates and fine chemical industries.

Properties

- Appearance: White solid

- Melting point:236-239 °C

- Boiling Point: 358.5±17.0 °C

- Density: 1.284 g/cm³

- Solubility: Soluble in dilute alkaline solutions, hot ethanol, and DMSO; slightly soluble in water.

- Storage temp:2-8°C

 

 

 

Specification

Items Specifications
Appearance white solid
Purity 99.1%min
Loss On Drying ≤ 0.5%
Heavy Metals ≤ 20 ppm
Water Content ≤ 0.1%
Residue on Ignition ≤ 0.2%

 

Applications

3-(3-pyridyl)acrylic acid (CAS: 1126-74-5) is a key intermediate for constructing the pyridineacrylic acid skeleton, and is widely used, especially in the synthesis of antithrombotic drugs.

  • Pharmaceutical Intermediates:
Ozagrel's key ingredient: This is the core application of the product. It is the direct prodrug of ozagrel sodium, an inhibitor of thromboxane synthase. This drug is widely used to treat acute thrombotic stroke and its sequelae, and it effectively inhibits platelet aggregation.
  • Organic Synthesis and Materials:

Photosensitive materials: Due to their conjugated double bond structure, they can be used to synthesize monomers for certain photosensitive polymers or photocurable resins.

Pyridine derivative synthesis: 3-pyridinepropionic acid can be synthesized by reducing carbon-carbon double bonds, or complex heterocyclic molecules can be constructed through other functional group transformations.

 

Package


  • #

Standard Packing:  25kg/cardboard drum (lined with polyethylene bag)

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