(S)-3-Aminobutanenitrile hydrochloride, with CAS number 1073666-54-2, is a high-purity chiral building block widely recognized as the key intermediate for the synthesis of the DPP-4 inhibitor Alogliptin (Benzoate). As a professional supplier, we utilize advanced asymmetric synthesis technology to guarantee exceptional optical purity (e.e. ≥ 99.5%) and stability. We adhere to strict moisture control measures during packaging and storage to ensure the product reaches our global customers in optimal condition.
Product Name :
(S)-3-Aminobutanenitrile hydrochlorideCAS No. :
1073666-54-2Application :
Orforglipron intermediatesOur (S)-3-aminobutanenitrile hydrochloride is a white to off-white crystalline powder and a high-purity chiral amine intermediate. It is a key starting material for the synthesis of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor. We employ advanced asymmetric synthesis and crystallization resolution technologies to ensure that the product has extremely high optical purity (e.e. ≥ 99.5%) and chemical stability, meeting the procurement needs of global pharmaceutical companies for high-standard chiral raw materials.
Properties
- Appearance: White solid
- Special properties: Extremely hygroscopic; readily absorbs moisture and clumps when exposed to air
- Molecular Weight: 120.58 g/mol
- Solubility: Easily soluble in water and methanol, slightly soluble in ethanol, and insoluble in diethyl ether.
- Storage temp:2-8°C
Specification
| Items | Specifications |
| Appearance | White solid |
| Purity | 99.5%min |
| Loss On Drying | ≤ 0.5% |
| Enantiomeric Excess, e.e. | ≥ 99.5% |
| Residue on Ignition | ≤ 0.1% |
| Water Content | ≤ 0.2% |
Applications
(S)-3-aminobutyronitrile hydrochloride (CAS: 1073666-54-2) is a core building block for constructing chiral drug molecules, and plays an irreplaceable role, especially in the synthesis of diabetes drugs.
This is the highest-value application of the product. It is used in the synthesis of alogliptin benzoate, a potent DPP-4 inhibitor used to treat type 2 diabetes. This intermediate provides the key (S)-configuration chiral center of the drug molecule.
It can be used as a general chiral amine source for the synthesis of other bioactive molecules or drug analogs containing (S)-3-aminobutyl structures.
Package

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